UCII : The groundbreaking collagen for healthy joints

UC-II® Outperforms Other Supplements in Healthy Joint Management

Several studies showed that UC-II® is 59% more effective than chondroitin and glucosamine in relieving dogs from pain and discomfort.

A study on 35 dogs showed that UC-II® could reduce joint pain and discomfort by up to 81%.

UC-II® outperformed glucosamine and chondroitin, as shown in the graph.
With UC-II®, improvement began after just 30 days and continued up to 150 days.

Clinical Study

UC-II's is Effective Through a Unique Process: Oral Tolerance

UC-II®, undenatured type II collagen, is effective through a particular and unique process: oral tolerance. 

When UC-II® reaches the gut, its 3-D structure allows it to be identified by Peyer patches, part of the immune system.

As a result, UC-II®triggers regulatory immune cells called T-Cells. These T-cells release anti-inflammatory molecules called cytokines, which help prevent cartilage collagen from breaking down.
Oral Tolerance reduces inflammation and facilitates cartilage repair, reducing dogs' pain and improving mobility.

Safe and Effective Way to Help your Joints

Two studies found that UC-II® improved mobility and reduced pain and discomfort, with efficacy similar to two different NSAIDs (anti-inflammatory medication).

After 30 days, results in mobility improvement and pain reduction were similar between UC-II® and Robenacoxib (anti-inflammatory medication)

UC-II® is one of the only ingredient found in supplement that has shown that type of result.

Like the other, this study is available online on Pubmed. 

Frequently Asked Questions on UCII

What is UC-II collagen?

UC-II undenatured type II collagen takes this a step further, thanks to a unique approach to improve joint mobility, comfort, and resilience. What sets UC-II apart is that it works effectively at a lower dose, tapping into the body's natural processes to support joint health without the need for high daily intakes.


What's the difference between types I, II, and III collagen?

There are at least 28 types of collagen, and three are particularly important for connective tissues.

  • Type I collagen: Predominantly found in skin, bones, and tendons, this type supports tissue strength and resilience, making it popular in beauty supplements.
  • Type III collagen: Often paired with Type I, Type III is found in muscles and blood vessels, aiding in tissue structure and elasticity.
  • Type II collagen: Key to joint health, Type II collagen is found in cartilage: the protective layer at the ends of bones that cushions them and reduces friction. This type of collagen helps joints withstand the daily wear and tear of movement, making it vital for maintaining mobility.

Why is type II collagen better for joint health?

Type II collagen is needed for joint structure, as it forms the backbone of cartilage. Cartilage provides a smooth, cushioned surface for joint bones to move against each other without friction.

Type II collagen levels decrease naturally with age, which may lead to joint discomfort and reduced flexibility.

UC-II undenatured collagen (undenatured means it retains its original structure and has not been broken down in any way) can help to counteract this by enhancing joint function, comfort, and resilience, even as natural collagen levels decline.

How does UC-II collagen work?

A single dose of UC-II collagen is only 40 mg, but it delivers results typically expected from much higher doses. Its unique mechanism, known as oral tolerance, sets it apart from other collagen products.

UC-II interacts with immune cells in the gut, initiating a process that protects existing cartilage from breakdown, while promoting the body's own collagen synthesis.

This mechanism allows UC-II to support joint health at low doses, in contrast to hydrolysed collagen types, which require larger amounts to achieve a similar benefit.

What does the science say about UC-II's effectiveness?

Studies have demonstrated UC-II's effectiveness in supporting joint health by improving comfort, flexibility, and mobility. A 2021 study conducted by Lonza, a leader in advanced ingredients for health products, confirmed UC-II's joint-supporting benefits.

This double-blind, placebo-controlled trial revealed that individuals taking UC-II experienced significant improvements in knee joint mobility and comfort during daily activities. Participants taking UC-II showed increased daily step counts and improved joint function, highlighting its effectiveness even at a low daily dose.

This research underscores UC-II collagen's unique mechanism and effectiveness, making it a scientifically supported option for those seeking enhanced joint health with the simplicity of a single small dose.

How else can Mobivox UC support joint health?

UC-II collagen is formulated with additional nutrients, including Rosehip extract, Sodium Hyaluronate, Curcumin C3 Complex & Vitamin C that further benefits joint health.

Rosehip Extract → Known for antioxidant properties that may help support joint comfort and mobility.
Christensen R, et al. Osteoarthritis Cartilage (2008)

Sodium Hyaluronate (Hyaluronic Acid) → Helps maintain joint lubrication and cushioning for smoother movement.
Altman RD, et al. Semin Arthritis Rheum (2015)

Curcumin C3 Complex® (Turmeric) → Contains bioactive compounds that may support joint flexibility through antioxidant action.
Daily JW, et al. J Med Food (2016)

Vitamin C → Contributes to normal collagen formation, essential for cartilage and overall joint health.
EFSA Scientific Opinion (2009)

Why do you need UC-II for an active lifestyle?